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Programmable and Modular Nucleic Acid Nanoassemblies-based (NAN) Platforms to Regulate Mechanosensitive Activation of T-cells

This technology includes mechanobiological nucleic acid nanoassemblies-based platforms with dynamically controlled efficiency of T-cell activation. T-cells are the central players in adaptive immune response led by a T-cell receptor (TCR) centric machinery. Current T-cell activation strategy (e.g., micron-scale beads) focuses on 2D TCR-agonist biomimetic...

Published: 8/12/2024 | Inventor(s): Kirill Afonin, Erdem Tabdanov, Alexander Zhovmer

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Category(s): Application > Research Materials, Collaboration Sought > Licensing