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Search Results - ajit+parhi
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Prodrugs and ADC Derivatives of Non-Camptothecin TOP1-Targeting Cancer Chemotherapeutics
Schematic Structure of an Antibody-Drug Conjugate (ADC) (en.wikipedia.org) Invention Summary: Topoisomerase 1 (Top1) is an essential enzyme in mammalian cells and is a validated target for the treatment of human cancers. Topotecan and irinotecan (camptothecin analogues) are two FDA approved Top1-targeted drugs. Despite being powerful anticancer drugs,...
Published: 12/4/2024
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Inventor(s):
Edmond LaVoie
,
Ajit Parhi
Keywords(s):
Anti-cancer
,
Small molecules
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Therapeutics