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BIS-Cyclic Guanidine Compounds as Novel Anti-Bacterial Agents

Competitive Advantages Low toxicity to human cells Potent anti-biofilm properties Effective against ESKAPE pathogens Summary By employing synthetic combinatorial libraries, our inventors have synthesized a class of bis-cyclic guanidine compounds that were found to have anti-bacterial activity against all six ESKAPE human pathogens....

Published: 8/26/2023 | Inventor(s): Marcello Giulianotti, Radleigh Santos, Renee Fleeman, Richard Houghten, Adel Nefzi, Lindsey Shaw

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Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical