Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use

Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use

Executive Summary:

Well-characterized non-genetically modified bovine primary muscle cell lines have been sorted based on genetic information and proliferate well for research use.

Background:

Animal cell lines are utilized for a variety of medical and veterinary research purposes. Bovine cells, in particular, are useful for studying bovine-related diseases and treatments

Description of Technology:

The muscle biology program at Michigan State University has developed over 100 high-quality primary muscle cell lines for research purposes. These non-genetically modified cell lines have been isolated from donor cattle using methodologies to generate cell lines with extended lifespans that have been sorted based on their genetic information. Cutting-edge methodologies are used to screen cells for viral and microbial contaminations. These cell lines store, ship, and thaw well, with viability and proliferation qualities being maintained under proper conditions.

Key Benefits:

• Non-genetically modified muscle cell lines with extended lifespans
• Cell populations are tested using a flow cytometer to confirm their purity
• Detailed background information on the donor animals is available, including stages from fetal (early, mid, late) to adult at 24 months; breed and sex (SNP-based determination)
• Cells are certified free from microbial and viral contaminants
• Cell phenotypes, growth, and fusion capabilities have been pre-tested.

Applications:

Bovine cell lines for research use

Protection Status:

             US Provisional Patent Application

Inventors:

             Dr. Jongkyoo Kim

MSU Technology Number(s):

             TEC2023-0089, TEC2023-0100