Synthetic Melanin Nanoparticles and Precursor Molecules as Hair Dyes

NU 2019-147

INVENTORS

• Nathan Gianneschi*
• Claudia Battistella

SHORT DESCRIPTION

A novel hair dyeing approach that utilizes synthetic melanin nanoparticles to deliver effective and long-lasting hair pigmentation. The method leverages temperature-controlled polymerization under mild, metal-free conditions for non-toxic and tunable color deposition.

BACKGROUND

Conventional hair dyes often depend on harsh chemicals, lengthy procedures, and metal-based catalysts that may cause toxicity and inconsistent coloration. Alternative nanoparticle-based methods have been explored but suffer from extended reaction times and limited color options, limiting their practical use. This invention overcomes these challenges by utilizing artificial melanin to provide a safe, rapid, and versatile hair dye solution.

ABSTRACT

This technology presents methods and materials for dyeing hair with artificial melanin. Artificial melanin precursors are contacted with an oxidizing agent in the presence of the hair, without relying on metal chelators or strong oxidants. Controlled polymerization occurs at temperatures equal to or greater than 30°C. Through modulation of reaction conditions such as temperature and solution composition, the process enables a broad color spectrum ranging from dark brown/black to orange/gold, making it applicable to diverse hair types, including blond, red, and previously dyed hair. The resulting pigmentation is both durable and persistent through multiple washing cycles, positioning this method as a commercially promising alternative to conventional hair dyes.

APPLICATIONS

• Professional salon treatments and at-home hair dye kits

ADVANTAGES

• Temperature-enhanced polymerization of melanin with rapid deposition and durable results.
• Allows customization of hair color by adjusting reaction parameters.
• Biocompatible and metal-free formulation ensures a safe, non-toxic approach suitable for repeated use.

PUBLICATIONS

• Battistella et al, Mimicking Natural Human Hair Pigmentation with Synthetic Melanin, ACS Central Science, 2020
• Battistella et al, Bioinspired Chemoenzymatic Route to Artificial Melanin for Hair Pigmentation, Chemistry of Materials, 2020

IP STATUS

• US Patent Pending 17/775,526