USF inventors have discovered novel therapeutic compounds that have shown to bind favorably to wild-type (WT) sortilin and increase glucose uptake, especially when used in conjunction with insulin. By stabilizing the proteins involved in the metabolic process, there is hope for a long-lasting, effective treatment for diabetic patients, especially ones suffering from obesity who are deficient in sortilin.
Comparison of Glucose Uptake Shows Significant Effect Over 24 hrs