Quantitative Large Area Binding Sensor For Detecting Biomarkers

Researchers at the University of Arizona have developed a lens-free holographic microscope (LFHM) for observing and quantifying target biomarkers in a solution, including targets with a large dynamic range in concentration. LFHM can be used to detect microscale targets (e.g., bacteria and cells) and nanoscale targets (e.g., viruses, DNA strands, and cancer biomarkers).

Advantages:

• Can image a large range of target sizes
• Accommodates a large dynamic range in concentration
• Has a large field of view

Applications:

• Cancer biomarker detection

Status: issued U.S. patent #11,879,830