Novel Methods for Making Pharmaceutical Drug Forms

Our researchers have discovered novel polymorphs, salts, hydrates, and solvate forms of these drugs and the process for their preparation. They have also provided a medicament of salt derivatives of these drugs as well as methods to  modulate their solubility and dose response.  This present invention provides the creation of drug derivatives improving drug properties such as bioavailability as well as methods for controlled release of said drugs, among many other advantages in drug delivery and treatment, has potential for treating patients with Alzheimer’s disease, breast cancer, HIV infection, diabetes, as well as numerous other diseases.

Competitive Advantages:

  • Improved bioavailability
  • Controlled release
  • Multiple diseases treated
  • Enhanced manufacturing of pharmaceutical salts

Figure shows a packing diagram of fluconazole benzene solvate

Desired Partnerships:

  • License
  • Sponsored Research
  • Co-development
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Pharmaceutical Forms, and Methods of Making and Using the Same Utility United States 10/599,010 8,436,029 3/17/2005 5/7/2013 3/17/2025