Immortalized Human Mesenchymal Stem Cell Line Overexpressing Thymidine Kinase Gene

Invetion Reference: 11/MED/454

There are over 10 million new cases of cancer every year. To fight this global health challenges, new treatment approaches, besides traditional strategies like chemotherapy and radiotherapy, are urged. Gene therapy is one of the promising approaches, but a safe and efficient delivery method to tumor site is necessary for its bench to bed side development. Mesenchymal stem cells (MSCs) are found in many fetal and adult tissues and can generate new cells either continuously during tissue development or remodeling or in response to injury stimuli. Tumor is considered as wounds that never heal, and tumor microenvironments have many similarities with the tissue repair processes that attract specific migration of MSCs (homing).

 
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