GL261 (mouse glioma 261) is an in vivo model system used to study glioblastoma multiforme (GBM). This technology is the GL261 cell line stably transfected with the luc2 gene (GL261-luc2) for the monitoring of intracranial mouse tumors. GL261-luc2 is a brighter version than the original GL261-luc line.
Relevant Paper: Abdelwahab MG, Sankar T, Preul MC, Scheck AC. Intracranial Implantation with Subsequent In Vivo Bioluminescent Imaging of Murine Gliomas. J. Vis. Exp. (57), e3403, DOI: 10.3791/3403, 2011.