This technology describes novel quaternary ammonium salt compounds with antibacterial properties and their methods of making.
Background Increased resistance to current antibiotics and QAS compounds exhibited by bacteria requires the discovery and production of new formulations. Moreover, the replacement of the benzyl functionality of traditional QAS bactericidals with a furyl group promises significant improvements in the sustainability of their production and use, as well as improved supply chain logistics, given that furfural is a broadly available raw material sourced from biomass.
Technology Description Quaternary ammonium salts (QAS) are bactericidal compounds that disrupt bacterial cell membranes, leading to lysis. These compounds are known efficient bactericidals, possessing bactericidal activity equivalent to that of benzalkonium chloride (BAC). The compositions described herein provide synthetic tunability, safety, and lower cost.
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Opportunity Oregon State University is seeking development partners for testing, scaling, and commercialization.
Status Patent application submitted 18/472,895