Compositions and Methods for Treating Stroke

Competitive Advantages

  • Reduces neural damage
  • Not dependent on type of stroke
  • Conivaptan is already FDA-approved
  • Greater therapeutic window than current stroke medications

Summary

USF researchers have developed a method of treating a stroke or suspected stroke by administering a pharmaceutical formulation comprised of conivaptan within 6 hours of stroke occurrence followed by an additional administration within a prescribed time period. Preliminary results have shown that this treatment method may reduce neuronal infarct size, neuronal edema and/or neuronal inflammation in a subject following a stroke. This method of treatment using a FDA-approved agent holds great therapeutic potential in stroke treatment.  

The Average Area Fraction of CD11b Staining at 48 Hours Post Stroke 

Desired Partnership

  • License
     
Patent Information: