Chromatographic Editing of Complex Mixtures

Competitive Advantages

  • Modifies complex extracts from plants
  • Prepare pharmaceutical compositions
  • Applicable to other complex mixtures

Summary

Our researchers have developed a method of modifying complex extracts in which components or mixtures of components are  selectively removed or added, thus providing a complex mixture that does not naturally occur. The method involves a selective deletion chromatography technique to prepare a composition which has a  refined therapeutic effect. The complex extract can be an extract obtained from one or more plants, e.g., an extract obtained from green tea leaves. This method can be used to prepare nutraceutical compositions, pharmaceutical compositions, and compositions for treating various conditions, including physiological dysfunctions associated with elevated reactive oxygen species and/or inflammatory molecule. 

Components from Green Tea Extract that Increase and Decrease Cellular ROS Levels and Should be Targeted with this Approach

Desired Partnerships

  • License
  • Sponsored Research
  • Co-Development

 

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Methods And Compositions For Modulating Complex Mixtures By Selective Deletion Chromatography Utility United States 16/050,621 11,478,524 7/31/2018 10/25/2022 4/11/2041