Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics

­PRODUCT OPPORTUNITIES

• Cell-membrane-coated, cargo-encapsulated polymer nanoparticles as target-specific prodrugs

PRODUCT OPPORTUNITIES

COMPETITIVE ADVANTAGES

• Enhanced cellular uptake and endosomal escape, resulting in more efficient delivery of therapeutics
• Enhanced selectivity of intracellular delivery of therapeutics

TECHNOLOGY DESCRIPTION

This invention provides cell-membrane-coated polymeric nanoparticles for efficient and selective intracellular delivery of therapeutics such as small molecule drugs, nucleic acids, and proteins.

ABOUT THE INVENTOR

Dr. Thayumanavan is a Distinguished Professor in the Department of Chemistry. He is a highly accomplished expert in organic and polymer chemistry and a prolific inventor. His research focuses on the design, synthesis and characterization of organic macromolecules of interest in supramolecular chemistry, materials science and biological applications. Dr. Thayumanavan has broad and well-established expertise in developing custom-designed molecules for specific end-use applications such as targeted delivery of therapeutics, smart sensors, and fuel cells.

AVAILABILITY:

Available for Licensing and/or Sponsored Research

DOCKET:

UMA 22-063

PATENT STATUS:

Patent Pending

NON-CONFIDENTIAL INVENTION DISCLOSURE

LEAD INVENTOR:

S. Thai Thayumanavan, Ph.D.

CONTACT:

This invention provides cell-membrane-coated polymeric nanoparticles for efficient and selective intracellular delivery of therapeutics such as small molecule drugs, nucleic acids, and proteins.