Aloe Vera-mediated tellurium nanoparticles with antibacterial and anticancer properties

INV-18121

 

Bacterial resistance to antibiotics has emerged as an increasing threat to health in society, due to the misuse of antibiotics and the development of bacterial strains with resistance. Data from the Centers for Disease Control (CDC) indicates that at least 2 million people become infected with antibiotic‑resistant bacteria in the United States annually, and of those, at least 23,000 people die as a consequence.

Therefore, novel approaches to combat antibacterial resistance to antibiotics need to be developed, especially those that do not require the use of antibiotics.

 

This technology provides an environmentally friendly and cost-effective approach for the synthesis of tellurium nanorods in aqueous media using an aloe vera extract as the reducing agent. Tellurium nanorods were characterized using Transmission Electron Microscopy and Energy‑Dispersive X‑Ray Spectroscopy to determine size, morphology, and composition. 

The nanorods were characterized and tested for their ability to inhibit bacterial growth. A decay in bacterial growth after 24 hours was achieved in both staphylococcus aureus and E. coli. Anti‑cancer properties were tested as well with human melanoma cells, and results indicated that the nanorods were able to delay cancer cell proliferation. 

 

- Provides a quick, cost‑effective, and green approach for the production of Tellurium nanorods

- Prevents antimicrobial resistance

- Effective against Gram‑positive and Gram‑negative bacteria

- Cell studies indicate antimicrobial and anticancer effects with low toxicity for healthy cells

 

- Antibacterial coatings for medical devices

- Antibacterial coatings for pipes

- Antibacterial treatment for healthcare acquired infections (HAIs)

- Cancer therapeutic applications

 

- License

- Partnering

- Research Collaboration