A Novel Expander for Drug Delivery in Cancer Patients

NU 2022-129

INVENTORS

  • John Yah Sung Kim*
  • Megan Fracol

SHORT DESCRIPTION

This invention offers a tissue expander that integrates drug delivery for breast reconstruction. It provides gradual inflation while releasing therapeutic agents to support improved healing.

BACKGROUND

Implant-based breast reconstruction is the most common method following mastectomy, accounting for over 75% of procedures in the United States. Surgeons face challenges with the two-stage process and high costs related to multiple surgeries. Current devices do not combine tissue expansion with localized drug delivery, leaving an unmet clinical need for improved patient outcomes.

ABSTRACT

The invention introduces a novel tissue expander that incorporates drug delivery functionality. It is designed to gradually inflate and form a breast pocket while simultaneously releasing therapeutic agents. Preliminary testing in controlled laboratory settings has shown that it meets target performance metrics for both tissue expansion and localized therapy, promising enhanced treatment outcomes for cancer patients undergoing reconstructive surgery.

MARKET OPPORTUNITY

The global breast reconstruction market was valued at over $615 million in 2023 and is projected to expand at a CAGR of 7.9% through 2030 (Source: Grand View Research, 2024)

DEVELOPMENT STAGE

TRL-4 - Prototype Validated in Lab: Key functions, including controlled inflation and drug release, have been successfully demonstrated in a laboratory environment.

APPLICATIONS

  • Tissue expansion in breast reconstruction: Assists in creating a suitable pocket for final implant placement.
  • Localized drug delivery: Facilitates targeted therapeutic release during the reconstruction process.

ADVANTAGES

  • Integrates dual functionality: Combines tissue expansion and drug delivery for streamlined treatment.
  • Reduces the need for multiple procedures: Minimizes additional interventions by merging two functions in one device.
  • Simplifies surgical workflow: Provides a more efficient process during breast reconstruction.
  • Enhances patient outcomes: Offers localized therapy that can reduce complications and support recovery.

IP STATUS

US Patent Pending

 

 

 

 

 

 

Patent Information: