A Method of Transdermal Drug Delivery Using Hyaluronic Acid Nanoparticles

USF researchers have developed novel hyaluronic acid and hyaluronic acid hybrid nanoparticles for transdermal drug delivery. These nanoparticles can encapsulate peptides, DNA, and small molecules. They also allow for the controlled release of the active molecules that they are transporting. The nanoparticles are at most 180 nm in diameter, making them an attractive candidate for cell specific drug delivery. These nanoparticles are made from natural polymers, are biocompatible and biodegradable, and are well suited for gene or chemotherapy treatment. 

  •     A controlled drug delivery release
  •     Produced from natural polymers
  •     Biocompatible and biodegradable
  •     Encapsulates DNA, peptides and other small molecules

An Example of a Solid Lipid Nanoparticle Used for Drug Delivery 

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Method of Transdermal Drug Delivery Using Hyaluronic Acid Nanoparticles Utility United States 11/279,956 7,371,738 4/17/2006 5/13/2008 4/17/2026