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Search Results - yugesh+kharel
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Composition and Methods for Preparing Orally Bioavailable Guanidine Prodrugs
THE CHALLENGE A major commercial hurdle in developing guanidine-based therapeutics lies in their poor oral bioavailability, which limits their effectiveness despite strong therapeutic potential. These compounds, while highly potent due to their ability to engage key molecular targets, struggle to reach the bloodstream when taken by mouth because of...
Published: 1/15/2026
|
Inventor(s):
Webster Santos
,
Christopher Sibley
,
Kyle Dunnavant
,
Christopher Shrader
,
Ariel Burgio
,
Kevin Lynch
,
Yugesh Kharel
Keywords(s):
Category(s):
Technology Classifications > Biomedical