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Methods of analyzing virus-derived therapeutics
Abstract: Researchers at the National Cancer Institute’s Biopharmaceutical Development Program recently developed massively parallel sequencing methods for virus-derived therapeutics such as viral vaccines and oncolytic immunotherapies. The methods allow for the determination of micro-heterogeneity and quantitation of low frequency sequence variants,...
Published: 7/29/2024   |   Inventor(s): Trevor Broadt, Michael Harwich, William Budd, Gregory Meyers
Keywords(s): MAPREC, massively parallel sequencing, MNVT, monkey neurovirulence safety testing, mutant analysis, oncolytic immunotherapy, restriction enzyme cleavage, RNA virus-derived, viral vaccines, virus-derived therapeutic
Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Immunology