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Search Results - technology+classifications+%3e+research+tools
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Fifth Harmonic and Five-Photon Excitation Fluorescence Multiphoton Microscopy
This technology introduces a fifth-order multiphoton microscopy system. This advanced method enables high-resolution, label-free imaging of biological samples using nonlinear optical effects. Laser scanning multiphoton microscopy has gained prevalence across a wide range of applications due to its high-resolution imaging potential. This system uses...
Published: 6/23/2025
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Inventor(s):
Khanh Kieu
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Sensors and Detection > Inspection
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Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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Technology Classifications > Engineering & Physical Sciences > Semiconductors
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Technology Classifications > Research Tools
Surface Enhanced Raman Spectroscopy (SERS) based sensing platform with machine learning
Invention Summary: Surface enhanced Raman spectroscopy (SERS) is a technique that can discriminate analyte molecules from the unique vibrational pattern they produce, which is correlated to their molecular structure. Identifying changes such as single base mutation in DNA, RNA and disease-specific microRNA biomarkers can facilitate early diagnosis...
Published: 6/10/2025
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Inventor(s):
Laura Fabris
,
Ahmed Aziz Ezzat
,
Jinisha Chheda
,
Yating Fang
Keywords(s):
Category(s):
Technology Classifications > Artificial Intelligence & Machine Learning
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Technology Classifications > Healthcare & Life Sciences
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Technology Classifications > Research Tools
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Technology Classifications > Sensors
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Technology Classifications > Software & Algorithms
Treadmill with Soft Ambulatory Surfaces
This invention is a specialized treadmill to study rat gait and mobility on simulated extraterrestrial terrains. This treadmill uses various harness-based gravity simulators and sensors for real-time physiological data collection. It can be used on a variety of ambulatory surfaces and used for many different applications. Background: Currently,...
Published: 6/9/2025
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Inventor(s):
David Margolis
,
Philipp Gutruf
,
Gerardo Figueroa Romero
,
Kevin Kasper
,
Gabriel Vogt
,
Avery Miller
,
Alicia Enriquez
,
Juan Campista
,
Will Stephenson
,
Alexis Barber
Keywords(s):
Category(s):
Technology Classifications > Research Tools
Predictive mRNA Biomarker for Progressive Coccidioidomycosis When Infected
This invention introduces a blood-based diagnostic test to assess coccidioidomycosis progression risk. The test is broken down into three overall steps: 1) blood collection, 2) ex vivo stimulation, and 3) mRNA quantification. This technology identified a predictive a gene set/biomarkers for coccidioidomycosis that was independently validated across...
Published: 5/19/2025
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Inventor(s):
John Galgiani
,
Yves Lussier
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Technology Classifications > Life Sciences > Biomarkers
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Technology Classifications > Research Tools
AI-Assisted Computational Prediction of Protein Functionality
This invention centers on creating a database and algorithms to explore protein functionality and interactions. The aim is to enable significant scientific discoveries, novel drug targeting, and the engineering of synthetic receptors like chimeric antigen receptors (CARs). By studying proteins involved in T cell activation over 450 million years of...
Published: 4/17/2025
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Inventor(s):
Michael Kuhns
,
Koenraad Van Doorslaer
,
Kevin Scott
,
Andrew Girvin
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Health IT
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Technology Classifications > Research Tools
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Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
microCafe: Revolutionizing Genomic Analysis with Large Language Models
Analyzing metagenomic (DNA) and metatranscriptomic (RNA) sequence data is technically challenging and time-consuming. This process often necessitates assembly and mapping sequencing reads to existing databases of target genomic information; however, these databases are memory intensive and frequently limited in scope. Additionally, the mapping and assembly...
Published: 4/1/2025
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Inventor(s):
Gholamali Rahnavard
,
Keith Crandall
Keywords(s):
Category(s):
Technology Classifications > Research Tools
Incubator Microplate Rack
This invention is a specialized incubator rack system designed to optimize cell culture in microplates by providing uniform growth conditions (equal airflow, humidity, and thermal conditions) for all plates regardless of their position in the stack. This rack ensures consistent growth conditions for cells compared to traditional incubator practices...
Published: 3/5/2025
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Inventor(s):
Matthew Kaplan
Keywords(s):
Category(s):
Technology Classifications > Research Tools
,
Technology Classifications > Life Sciences
Colorectal Cancer Prognostic/Prediction
This technology provides a gene score system to assess the effectiveness of antifibrotic treatments on colorectal cancer (CRC). By comparing gene expressions from colorectal cancer cells under two different types of mechanical conditioning, this system identifies specific gene signatures that correlate with an increased risk of metastasis and lower...
Published: 4/1/2025
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Inventor(s):
Ghassan Mouneimne
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Oncology
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Technology Classifications > Life Sciences > Biomarkers
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Technology Classifications > Life Sciences > Diagnostics
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Technology Classifications > Research Tools
Real-Time Battery Health and Charge Diagnosis via Thermal Conductivity/Diffusivity Analysis
A flexible thin-film sensor is installed on a LIB cell for the thermal conductivity/diffusivity measurement. The sensor has patterns that can deposit heat and measure local temperature simultaneously. Invention Summary: The reliable measurement of a battery’s state of health (SOH) and state of charge (SOC) is critical in battery management...
Published: 12/3/2024
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Inventor(s):
Amin Reihani
Keywords(s):
Category(s):
Technology Classifications > Energy & Battery
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Technology Classifications > Physical Sciences & Engineering
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Technology Classifications > Sensors
,
Technology Classifications > Software & Algorithms
,
Technology Classifications > Research Tools
SuperSelective PCR Primers
Structure of a SuperSelective primer for the detection and quantitation of rare mutant sequences in the presence of 1,000,000 wild-type sequences; and a demonstration that the number of amplification cycles required to generate a signal above background is inversely linearly proportional to the logarithm of the number of mutant molecules in the original...
Published: 4/17/2025
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Inventor(s):
Salvatore Marras
,
Diana Vargas-Gold
,
Sanjay Tyagi
,
Fred Kramer
Keywords(s):
Anti-cancer
,
Sensors & Probes
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Research Tools
,
Technology Classifications > Diagnostics
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