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NOVEL HIGH RESOLUTION MULTI-FUNCTION AND CONFORMAL ELECTRONICS DEVICE FOR DIAGNOSIS AND TREATMENT OF CARDIAC ARRHYTHMIAS
­ Localization and treatment of arrhythmia using Balloon Catheterization method Arrhythmias is a cardiac condition that affects 1.5 to 5% of the American population and a leading cause of cardiac incidents and death. As arrhythmia is a paroxysmal condition, accurate detection of affected area and targeted treatment is paramount for recovery. ...
Published: 7/30/2024   |   Inventor(s): Igor Efimov, Kedar Aras, Erdit Gremi, John Rogers
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Cardiology
Wearable Personal Auscultation Device
Wearable Auscultation device for continuous Chest sound monitoring Researchers at George Washington University have a developed a novel device that can continuously monitor auscultations, which works as a replacement for a stethoscope. The device uses microphones, microcontrollers, audio filters, signal amplification devices, data storage and Bluetooth....
Published: 7/30/2024   |   Inventor(s): Richard Downen, Zhenyu Li
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices
Apparatus for Automated Nerve Identification with Polarimetric Imaging and Artificial Intelligence
Researchers at GW have developed a novel solution to identify nerve tissues that can allow an accurate effective performance of a nerve-related surgery. The novel solution is based on a deep-learning network framework that utilizes a U-Net architecture with a Transformer block based fusion module at the bottleneck. The identification of nerve tissues...
Published: 7/30/2024   |   Inventor(s): Chung Hyuk Park, Gary Milam, Baijun Xie
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Diagnostic Devices
Multimodal Multilayered Soft Electronics in Advanced Devices
Researchers at GW have invented an electronic system for multimodal diagnostic measurements and therapeutic interventions. The electronic system allows a higher spatial density for the placement of sensors and actuators, thus resulting in a better interface aspect for delivering drugs between any respective contact tissue and any respective portion...
Published: 7/30/2024   |   Inventor(s): Igor Efimov, Mengdi Han, Roozbeh Ghaffari, John Rogers
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software > Processing Chips, Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices, Technology Classifications > Medical Devices > Therapeutic Devices
Triple-Parametric Optical Mapping for Simultaneous Measurement of Transmembrane Potential, Intracellular Calcium and NADH
Researchers at GW have developed a novel triple-parametric optical mapping method that can effectively, accurately, and simultaneously measure metabolic, electrical, and contractile components associated with cardiac physiology. As a result, this allows effective clinical management of cardiac procedures especially with regards to one aspect known in...
Published: 7/30/2024   |   Inventor(s): Igor Efimov, Sharon George
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices > Therapeutic Devices
Selective His Bundle Mapping and Pacing Method and Device
Researchers at GW have developed a system that can effectively and accurately allow a respective practitioner to place a “His Bundle Pacing” electrode on a subject’s heart as part of various known cardiovascular procedures. In particular, the system can include a bioelectronic catheter having at least one multilayer electronic array...
Published: 7/30/2024   |   Inventor(s): Igor Efimov, Jaclyn Brennan, John Rogers
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices, Technology Classifications > Medical Devices > Surgical
FAST LABEL-FREE METHOD FOR MAPPING CARDIAC PHYSIOLOGY
­Researchers at The George Washington University are developing a fast label-free mapping system of excitation-contraction-metabolic waves at hundreds to thousands (e.g., 100-5,000) of frames per second for mapping cardica physiology. Such a system allows for clinical mapping of atrial and ventricular arrhythmia during, or prior to, ablation procedures...
Published: 7/30/2024   |   Inventor(s): Igor Efimov, Jaclyn Brennan
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology
Thick 3D Bioprinted Cardiac Patch with Anisotropic and Perfusable Vessels
GW researchers fabricated a vascularized patch of cardiac tissue suitable for cardiac regeneration using 3D bioprinting. Cardiovascular disease involving myocardial infarction is a major cause of morbidity and mortality worldwide. Following myocardial infarction, adult cardiac tissue cannot significantly repair or regenerate itself. Current therapies...
Published: 7/30/2024   |   Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology
MitoScope: Minimally Invasive Device for Measuring the Energy Production Rate of Heart Tissue
The minimally invasive MitoScope assesses the metabolic rate of heart tissue in vivo, non-destructively, and in real-time. MitoScope measures the mitochondrial enzyme activity of the heart to provide unique insight that could improve the treatment of heart failure, coronary heart disease, diabetes, and many other diseases that alter myocardial metabolism....
Published: 9/11/2024   |   Inventor(s): Matthew Kay, Angel Moreno, Rafael Jaimes, III
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology
Small molecules to prevent HIV-associated coronary artery disease
HIV-infected patients have high risk of coronary artery disease (CAD). Previously, GW researchers identified HIV regulatory protein Nef as a causative factor in foam cell formation, a precursor condition to CAD. Currently, GW researchers developed compounds that show Nef-neutralizing effects in vitro. The prototype compounds restore cholesterol efflux...
Published: 9/11/2024   |   Inventor(s): Michael Bukrinsky, Ruth Hunegnaw, Alexei Adzhubei
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Therapeutics > Cells
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