Search Results - technology+category+%3e+drug+screening

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Methods For The Prediction Of Drug Penetration and Exposure In The Human Brain
Description: A novel 9‑compartment physiologically based pharmacokinetic model was developed and fully validated for prediction of heterogeneous drug distribution and exposure in the human central nervous system (CNS) and brain tumors. The 9-compartment model accounts for the general anatomical structure and pathophysiology of the human CNS and brain...
Published: 11/21/2025   |   Inventor(s): Jing Li, Seongho Kim, Charuka Wickramasinghe
Keywords(s):  
Category(s): Technology Category > Life Science, Technology Category > Method, Technology Category > Drug Screening, Technology Category > Drug Delivery
Generation of gp78 null mice
Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...
Published: 9/15/2025   |   Inventor(s): Avraham Raz, Andrei Golovko
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Oncology, Technology Category > Life Science, Technology Category > Genomics/Genetics, Technology Category > Drug Screening, Technology Category > Drug Delivery, Technology Category > Drug Discovery, Technology Category > Biomedical, Technology Category > Biotechnology, Technology Category > Biology, Technology Category > Animal models