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Search Results - swaminathan+iyer
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Specific PD-1 DNA Aptamers as Immunotherapeutic Agents in the Treatment of Cancers
The invention are therapeutic PD-1 DNA aptamers used to block PD-1 activity and enhance T-cell cytotoxicity against leukemias and solid tumors. Stage of Development In vitro data: Several aptamers were developed using SELEX technology against endogenous immunoprecipitated PD-1 and they were found to have highly conserved regions using high throughput...
Published: 3/12/2024
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Inventor(s):
Swaminathan Iyer
,
Santhana Thankgavelu Devaraj
Keywords(s):
Category(s):
Clinical Area > Cancer
,
Research Area > Cancer
,
Technology Classifications > Therapeutic > Immunotherapy