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Sirt6 LoxP (Sirt6tm1.1Cxd) Mouse Model for Liver Studies
Generation of floxed Sirtuin 6 for the construction of conditional knockout mice. The Sirtuins (Sirt1-7), a family of seven proteins related to yeast Sir2, are histone deacetylases that regulate many critical biological processes including genomic stability, adaptation to calorie restriction and aging. Mice with a targeted disruption of Sirt6 had very...
Published: 10/28/2024   |   Inventor(s): Chuxia Deng
Keywords(s): IDXXXX, IXXXXX, LOXP, Mouse, Sirt6, Sirt6tm1.1Cxd, Tm1.1Cxd
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics