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Search Results - single+domain+antibodies+(sdab)
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Single domain CD4, HIV-1 Antibodies, and Fusion Proteins for treatment of HIV
Abstract: Soluble forms of human CD4 (sCD4) inhibit HIV-1 entry into immune cells. Different forms of sCD4 and their fusion proteins have been extensively studied in animal models and clinical trials as promising HIV-1 inhibitors. However, they have not been successful in clinical trials due to their transient efficacy. sCD4 is also known to interact...
Published: 5/22/2024
|
Inventor(s):
Dimiter Dimitrov
,
Weizhao Chen
Keywords(s):
CD4
,
Dimitrov
,
fusion protein
,
HIV-1
,
Single Domain Antibodies (sdAb)
Category(s):
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
,
Collaboration Sought > Licensing