Search Results - sabyasachi+sen

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(Technology Bundle) Stem cells with transiently reduced p53 to treat diabetes associated kidney disease and peripheral vascular disease
Local delivery of endothelial progenitor cells (EPCs) may treat diabetic-related kidney disease (DKD) and peripheral vascular disease (PVD). EPCs may be obtained from a patient’s peripheral blood. The hyperglycemic state in diabetic patients causes transplanted EPCs to undergo apoptosis, creating a challenge for such therapies. By transiently...
Published: 6/11/2026   |   Updated: 6/11/2026   |   Inventor(s): Sabyasachi Sen
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells
(Technology Bundle) Stem cells with transiently reduced p53 to treat diabetes associated kidney disease and peripheral vascular disease
Local delivery of endothelial progenitor cells (EPCs) may treat diabetic-related kidney disease (DKD) and peripheral vascular disease (PVD). EPCs may be obtained from a patient’s peripheral blood. The hyperglycemic state in diabetic patients causes transplanted EPCs to undergo apoptosis, creating a challenge for such therapies. By transiently...
Published: 6/11/2026   |   Updated: 6/11/2026   |   Inventor(s): Sabyasachi Sen
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells
Cell‑Free Exosome Therapy to Rebuild Kidney Function in Diabetes
Chronic kidney disease (CKD), particularly in patients with diabetes, represents a large and growing unmet medical need, affecting tens of millions of people worldwide and leading to progressive loss of kidney function, cardiovascular complications, and high mortality. In diabetic CKD, persistent high blood sugar damages the endothelial cells that line...
Published: 6/3/2026   |   Updated: 6/3/2026   |   Inventor(s): Sabyasachi Sen
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides