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Search Results - robert+grams
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PhAzE chemistry for selective covalent modification of protein tyrosine and lysine residues
PhAzE chemistry uses cell-permeable phospho-triazole reagents to covalently bond tyrosine and lysine residues in proteins, mimicking natural phosphorylation with low toxicity and tunable reactivity, enabling chiral probe design and potential RNA targeting. Background Covalent chemistry has become a cornerstone of modern chemical biology and drug discovery,...
Published: 6/4/2026
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Updated: 6/4/2026
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Inventor(s):
Ku-Lung Hsu
,
Robert Grams
Keywords(s):
Category(s):
Life sciences > Research tools > Reagent
,
Life sciences > Therapeutics > Formulation