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Allosteric Proteasome Inhibitors for Treatment of Cancer
UT Health San Antonio scientists have discovered novel small-molecule compounds that have allosteric signaling activity to modulate proteasome catalytic activity. The allosteric proteasome inhibitors can be used alone or in combination with existing competitive proteasome inhibitors for the treatment of cancer. Studies of combination treatment demonstrate...
Published: 5/14/2024   |   Inventor(s): Pawel Osmulski, Maria Gaczynska
Keywords(s):  
Category(s): Therapeutics > Small Molecule, Clinical Specialty > Oncology