Search Results - patient+stratification

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A Gene-Based Prognostic for Hepatocellular Carcinoma Patient Response to Adjuvant Transcatheter Arterial Chemoembolization
Abstract: Hepatocellular Carcinoma (HCC) is one of the most common cancers worldwide with largely unfavorable outcomes due to a lack of effective treatment options for patients in the later state of disease. The gold standard of care for HCC patients with intermediate to locally advanced tumors is transcatheter arterial chemoembolization (TACE), a procedure...
Published: 4/8/2024   |   Inventor(s): Xin Wei Wang, Valerie Miller
Keywords(s): Gene-Expression Signature, hepatocellular carcinoma, Patient Stratification, prognostic
Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Synthetic Lethality-mediated Precision Oncology via the Tumor Transcriptome
Abstract: The use of tumor transcriptomics for precision oncology has made significant advances, mainly by identifying cancer driver genes or actionable mutations for treatment with targeted therapies.  However, this strategy misses out on broader genetic interactions that could reveal additional biologically testable biomarkers for therapy response...
Published: 4/8/2024   |   Inventor(s): Eytan Ruppin, Joo Lee
Keywords(s): Genetic Interactions, Patient Stratification, Precision Diagnostics, Precision Oncology, Ruppin, Synthetic Lethality, Transcriptome
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology