Search Results - nicholas+klemen

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Resting-State Functional Magnetic Resonance Imaging Derived From Dynamic Perfusion Imaging (Case No. 2023-126)
Intro Sentence: UCLA researchers in the Department of Radiology have developed a novel method for obtaining simultaneous perfusion and functional MRI data from a single MRI acquisition to improve the diagnosis, monitoring, and management of brain tumors and stroke. Background: Advanced magnetic resonance imaging (MRI) techniques are crucial for...
Published: 10/23/2024   |   Inventor(s): Benjamin Ellingson, Nicholas Cho, Chencai Wang
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Monitoring And Recording Systems
Methods of Producing Thymic Emigrants from Induced Pluripotent Stem Cells
Abstract: Hematopoietic and pluripotent stem cells can be differentiated into T cells with potential clinical utility. Current approaches for in vitro T cell production rely on Notch signaling and artificial mimicry of thymic selection. However, these approaches result in unconventional or phenotypically aberrant T cells; which may lead to unpredictable...
Published: 4/8/2024   |   Inventor(s): Raul Sakoda, Nicholas Klemen, Nicholas Restifo
Keywords(s): DIFFERENTIATION, Induced Pluripotent Stem Cells, IPSCS, RESEARCH MATERIAL, Restifo, T Cells, Thymic Environment, Tool
Category(s): TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing