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Liver Organoids with Multi-Lineage Cellular Repertoire
This invention is a human liver organoid model derived from induced pluripotent stem cells (iPSCs) that replicates the cellular complexity of the human liver. The system is designed to include multiple liver cell types, without genetic manipulation or animal derived matrices, enabling more accurate modeling of liver diseases such as Metabolic Dysfunction-Associated...
Published: 8/18/2025   |   Inventor(s): Jason Wertheim, Ekta Minocha, Ashwani Gupta, John Purdy, Nate Schmidt, Richard Green
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Life Sciences, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Simulators and Modeling Tools