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MUC-1 Tumor Antigen Agonist Epitopes for Enhancing T-cell Responses to Human Tumors
Abstract: The MUC-1 tumor associated antigen has been shown to be overexpressed and/or underglycosylated in a wide range of human cancers.  The C-terminus region of MUC-1 (MUC-1C) has been shown to be an oncogene and has been associated with a more aggressive phenotype in several different cancers. Scientists at NIH have identified 7 new agonist epitopes...
Published: 4/8/2024   |   Inventor(s): Jeffrey Schlom, Kwong-Yok Tsang
Keywords(s): AGONIST, ANTIGEN, Epitope, MUC-1
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Therapeutics