Search Results - morpholino

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Modulating Chemotherapeutic Cytotoxicity
Abstract: Many chemotherapeutic agents cause significant cytotoxicity to non-cancer ("normal") cells, resulting in undesirable side-effects and often limiting the dose and/or duration of chemotherapy that can be administered to a patient. Investigators at the National Cancer Institute’s Laboratory of Pathology have demonstrated that deficiency or blockade...
Published: 4/22/2025   |   Inventor(s): David Roberts, David Soto Pantoja
Keywords(s): CD47, morpholino
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology
Morpholino Oligomers to Prevent and Treat Coronavirus Infection
This technology licensing opportunity relates to antisense agents for treating or preventing a SARS-CoV-2 infection. The antisense agents are peptide-conjugated morpholino oligomers targeting pre-mRNA of a host (human) gene that encodes a protease. Some antisense agents included within the scope of this technology include agents previously shown to...
Published: 7/30/2025   |   Inventor(s): Hong Moulton, David Stein, Eva Bottcher-Friebershauser
Keywords(s): Morpholino, SARS-CoV-2, Therapeutic
Category(s): Therapeutics