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Search Results - michael+mcintosh
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Oncolytic Dual Targeting Agent for Treating Diseases Associated with the Epstein-Barr Virus (EBV)
Identifies and Eliminates Specific Enzymes that Cause Cell Growth in EBV-Associated Cancers This dual targeting agent reactivates the Epstein-Barr virus (EBV) to treat cancer patients by targeting enzymes that support the EBV latent state and thereby, uncontrolled EBV-cancer cell growth. The Epstein-Barr virus is a human herpesvirus infecting most...
Published: 1/20/2026
|
Inventor(s):
Sumita Bhaduri-McIntosh
,
Yufeng Xiao
,
Guangrong Zheng
,
Michael McIntosh
,
Beth Rousseau
Keywords(s):
Category(s):
Technology Classifications > Human Health Care
,
Technology Classifications > Human Health Care > Therapeutics
Bruton's Tyrosine Kinase (BTK) Inhibitors as Antiviral Agents via Inflammasome Blockade
Proactively Mitigates and/or Prevents EBV-Driven Malignancies in Immunosuppressed Patients This approach prevents EBV-associated malignancies by inhibiting the Epstein-Barr virus (EBV) lytic phase malignancies. EBV is a ubiquitous oncogenic herpesvirus, causing an estimated 300,000 new cancers and 200,000 deaths each year. EBV commonly causes infectious...
Published: 1/20/2026
|
Inventor(s):
Sumita Bhaduri-McIntosh
,
Michael McIntosh
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
11-Gene Panel That Predicts if a Cancer Will Respond to Synthetic-Lethal Therapies
Identifies a Wide Range of Cancers That Will Succumb to PARP Inhibitors Already Used Successfully in Ovarian and Breast Cancer This STAT3-induced 11-gene signature can predict which cancers will respond to synthetic lethal therapies, such as poly ADP-ribose polymerase (PARP) inhibitors that have been successfully used in ovarian and breast cancer....
Published: 1/20/2026
|
Inventor(s):
Sumita Bhaduri-McIntosh
,
Michael McIntosh
,
Siva Koganti
,
Xiaofan Li
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Medical Devices > Others