Search Results - michael+bukrinsky

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AIBP-Driven Lipid Raft Modification: A Novel Approach for HIV Treatment
COVID-19 and HIV remain significant global health challenges, with millions of people affected worldwide. Despite the availability of treatments, both viruses continue to spread, and neither has a definitive cure. A key issue lies in the viruses’ ability to exploit host cellular mechanisms, such as lipid rafts—specialized regions in cell...
Published: 12/10/2024   |   Inventor(s): Michael Bukrinsky, Dmitri Sviridov, Yury Miller
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides
Small molecules to prevent HIV-associated coronary artery disease
HIV-infected patients have high risk of coronary artery disease (CAD). Previously, GW researchers identified HIV regulatory protein Nef as a causative factor in foam cell formation, a precursor condition to CAD. Currently, GW researchers developed compounds that show Nef-neutralizing effects in vitro. The prototype compounds restore cholesterol efflux...
Published: 9/11/2024   |   Inventor(s): Michael Bukrinsky, Ruth Hunegnaw, Alexei Adzhubei
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Therapeutics > Cells