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Small molecule inhibitor of ARID4B to combat endocrine therapy resistance in breast cancer
Large-scale genomic analyses, including data from The Cancer Genome Atlas (TCGA) and other breast cancer datasets, have identified amplification of the AT-rich interactive domain 4B (ARID4B) protein, also known as retinoblastoma binding protein 1-like 1 (RBP1L1), in approximately 22% of human breast cancer cases. Compelling clinical evidence highlights...
Published: 8/20/2024   |   Inventor(s): Samuel Awuah, Mei-Yi Wu, Ray-Chang Wu, Samuel Ofori
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Therapeutics