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Search Results - mark+nelson
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T-Type Calcium Channel Enhancer for TAF1 Associated Neurological Defects
This invention relates to TAF1-ID animal model and new use for SAK3 which was first developed as a T-type voltage gated Ca2+ channel enhancer for treating TAF1 intellectually disability (TAF1 ID) syndrome, an x-linked disorder caused by loss-of-function mutations in the TAF1 gene. Background: TATA-box binding protein associated factor 1 (TAF1) plays...
Published: 11/16/2023
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Inventor(s):
Mark Nelson
,
Rajesh Khanna
,
Janakiraman Udaiyappan
,
Dhanalakshmi Shankara Raman
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences
,
Technology Classifications > Life Sciences > Therapeutics