Search Results - life+science+venture%2fearly

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Metadherin: Therapeutic Target for Treating Primary and Metastatic Cancer and Combating Chemoresistance
Princeton Docket # 07-2399 Researchers in the Molecular Biology Department at Princeton University have identified a recurrent 8q22 genomic gain in poor-prognosis human breast cancers, which harbors the metastasis gene Metadherin (MTDH). Genomic gain of 8q22 elevates expression of MTDH, which is overexpressed in more than 40% of breast cancers...
Published: 9/6/2022   |   Inventor(s): Yibin Kang, Guohong Hu
Keywords(s): Biotechnology/Pharmaceuticals, cancer/oncology, drug target, life science venture/early
Category(s): Medical Devices/Diagnostics, Biotechnology/Pharmaceuticals
Jagged1, a marker and therapeutic target for breast cancer bone metastasis
Princeton Docket # 11-2669 Although several molecular contributors of bone metastasis have been identified, effective therapies still await a more comprehensive understanding of the complex molecular and cellular networks of tumor stromal interactions in bone metastasis. Researchers in the Department of Molecular Biology, Princeton University...
Published: 3/30/2022   |   Inventor(s): Yibin Kang, Nilay Sethi
Keywords(s): biomarker/diagnostic, cancer/oncology, drug target, life science venture/early
Category(s): Medical Devices/Diagnostics, Biotechnology/Pharmaceuticals