Search Results - jennifer+koevary

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Companion Diagnostic for Immunomodulatory Repair Treatments
This technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025   |   Inventor(s): Steven Goldman, Daniel Benson, Adrian Grijalva, Jordan Fink, Jordan Lancaster, Jennifer Koevary, Simar Singh
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Healthcare Portfolios > Heart and Vascular
Mechanism of Tissue Regeneration
This invention is a biodegradable patch seeded with human neonatal dermal fibroblasts and human-induced pluripotent stem cell-derived cardiomyocytes, which helps regenerate endogenous cardiomyocytes in adult murine, rat and swine models of myocardial infarction as a cause of chronic heart failure (CHF). This invention details changes in specific gene...
Published: 2/3/2025   |   Inventor(s): Steven Goldman, Jennifer Koevary, Jordan Lancaster, Jordan Fink, Adrian Grijalva
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Life Sciences > Therapeutics
Clinical ECG Parameters from a Bioengineered Human Cardiac Tissue
This technology consists of a bioengineered cardiac tissue that exhibits electrocardiogram parameters and can be used in screening cardiotoxicity and proarrhythmic potential. Background: Currently, pharmaceutical compounds must be screened for cardiotoxicity using in vitro testing and animal models. However, current cell-based methods rely on cell...
Published: 4/3/2023   |   Inventor(s): Ikeotunye Chinyere, Jordan Lancaster, Jennifer Koevary, Steven Goldman
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Materials > Biomaterials