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Alpha-galactosidase-A Knockout Mouse Model for Studying Fabry Disease
This technology includes an alpha-galactosidase-A knockout mouse model that can be used to study Fabry disease, an X-linked lysosomal storage disorder. Alpha-galactosidase-A is a crucial enzyme responsible for the breakdown of glycolipids, particularly globotriaosylceramide (Gb3), within lysosomes. In Fabry disease, a rare and inherited lysosomal storage...
Published: 4/8/2024
|
Inventor(s):
Toshio Ohshima
,
Ashok Kulkarni
,
Roscoe Brady
,
Gary Murray
Keywords(s):
Category(s):
Application > Research Materials
,
Application > Therapeutics
,
Application > Vaccines
,
Collaboration Sought > Materials Available
,
ResearchProducts > Animal Models
,
TherapeuticArea > Rare / Neglected Diseases
,
TherapeuticArea > Metabolic Disease