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New Cholera Vaccine and Method for Conjugating Bacterial Polysaccharides to Proteins
A new conjugate vaccine for cholera has been developed. The invention includes a new method to conjugate the O-specific polysaccharide-core part of the bacterial lipopolysaccharide and protein subcomponents. Conventional technology has entailed chemical treatment of both components to introduce linkers, which made them amenable for covalent linking....
Published: 10/28/2024   |   Inventor(s): Peng Xu, Mohammed Alam, Anuj Kalsy, Richelle Charles, Stephen Calderwood, Dwight Peterson, Edward Ryan, Firdausi Qadri, Willie Vann, Pavol Kovac
Keywords(s): Amines, CONJUGATING, DA3XXX, DAXXXX, DC4XXX, DCXXXX, DEXXXX, DXXXXX
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Vaccines