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Engineered enzyme therapy for targeted reduction of plasma homocysteine in metabolic disorders
This technology is a specially engineered human enzyme, modified and PEGylated to break down excess homocysteine in the blood, offering a new treatment for homocystinuria and hyperhomocysteinemia with improved effectiveness and dosing flexibility. Background Homocystinuria and hyperhomocysteinemia are metabolic disorders characterized by elevated...
Published: 1/27/2026
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Inventor(s):
Scott Rowlinson
,
Christopher Daige
,
Leslie Sloan
Keywords(s):
Category(s):
Life sciences > Therapeutics > Small molecule