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Search Results - chelsea+massaro
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Covalent ERK inhibitors for suppressing cancer
BI-78D3, a small molecule, covalently binds to ERK1/2’s D-recruitment site, disrupting ERK signaling crucial for cancer cell growth. This shows promise for treating ERK-dependent cancers, including those resistant to BRAF inhibitors. This disrupts ERK signaling crucial for cell proliferation and survival, particularly in certain cancers like...
Published: 11/8/2024
|
Inventor(s):
Kevin Dalby
,
Ramakrishna Edupuganti
,
Tamer Kaoud
,
Chelsea Massaro
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug delivery
,
Life sciences > Therapeutics