Search Results - charles+mace

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Functional Point-of-Care Dried Blood Spot Cards
SUMMARY OF PROBLEMCurrently, blood is collected and stored for further analysis on dried blood spot (DBS) cards. Uses include testing expecting mothers for fetal distress, and newborns for metabolic and congenital disorders; and is a field standard for biobanking and epidemiology.However, these cards are subject to sampling inconsistencies. Under- or...
Published: 7/7/2022   |   Inventor(s): Charles Mace, Jessica Brooks, Syrena Fernandes, Keith Baillargeon
Keywords(s):  
Category(s): Device, Diagnostic
Aqueous 2-Phase System for the Separation and Recovery of Mammalian Cells from Contaminated Cultures
SUMMARYTufts researchers have developed a method to separate cultured mammalian cells from contaminants based on density using aqueous two-phase systems (ATPS) which allows recovered cells to be cultured after decontamination without the need for antibiotic treatments.PROBLEMThe in vitro culture of mammalian cells is a crucial part of biomedical research....
Published: 9/30/2020   |   Inventor(s): Charles Mace, Christopher Luby
Keywords(s):  
Category(s): Device
Fluidic Devices Involving Signal Generation at Converging Fronts
DESCRIPTIONDr. Charles Mace has designed a novel multilayered paper device. First, liquid sample is transported to chambers within the device with stored reagents. Then the liquid mixtures from the chambers converge back to a reaction zone. The converging liquid fronts generate a signal that, through design and specific paper treatments, restrict signal...
Published: 9/30/2020   |   Inventor(s): Charles Mace, Daniel Wilson
Keywords(s):  
Category(s): Device, Diagnostic
Separation of Cells Based on Size and Affinity Using Paper Microfluidic Devices
SUMMARYTufts University investigator Charles Mace has developed a novel paper device that can be used to separate and quantify blood based on size exclusion and affinity separation. This technology is ideal for applications in personalized healthcare, point-of-care diagnostics, monitoring of livestock, and determining food or water quality.PROBLEMA...
Published: 7/7/2022   |   Inventor(s): Charles Mace, Syrena Fernandes, Samuel Berry
Keywords(s):  
Category(s): Device, Diagnostic