Search Results - central+nervous+system+(cns)

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Synthetic engineered potassium channel (EKC) for gene therapy
Available For: Licensing<h2>Summary</h2>{{start}} Epilepsy affects around 60 million people globally and there remains an urgent need for novel treatment methods. Researchers at UCL Institute of Neurology have developed a novel synthetic engineered potassium channel (EKC) as a gene therapy tool to treat epilepsy and other neurological conditions....
Published: 9/18/2024   |   Inventor(s): Stephanie Schorge, Albert Snowball, Elodie Chabrol, Dimitri Kullmann, Matthew Walker
Keywords(s): Central Nervous System (CNS)
Category(s): Gene/Cell Therapy
Tau-gene-specific non-coding RNA genes for the therapeutic reduction of tau levels
Available for: Exclusive/Non-Exclusive licensing<h2>Summary</h2>{{start}} During genome transcription, both coding and non-coding transcripts are generated with a wide range of both size and coding potential. Among these are long non-coding RNA (lncRNA) genome transcripts, some of which are antisense to protein-coding genes (AS-lncRNAs)....
Published: 9/18/2024   |   Inventor(s): Rohan De Silva, Roberto Simone
Keywords(s): Central Nervous System (CNS)
Category(s): Therapeutic
Drug Delivery System for Crossing the Blood Brain or Blood Retinal Barrier (UDDS)
Available For: Exclusive licensing<h2>Summary</h2>{{start}} The blood retinal barrier (BRB), and the blood brain barrier (BBB), represent a significant impediment to drug delivery to the eye and the brain, respectively. This lack of drug penetration has resulted in diseases, such as Age-related Macular Degeneration (AMD), Alzheimer's Disease...
Published: 9/18/2024   |   Inventor(s): Francesca Cordeiro, Stephen Moss, Katy Coxon (now Dalchau), James Duggan
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Delivery of Drugs/Molecules, Regenerative Medicine
Voltage-Gated Sodium Channel Knockout Mice: Tools for Developing Therapeutics for the Treatment of Pain
Available for: Non-exclusive licensing<h2>Summary</h2>{{start}} Scientists at University College London have developed Voltage-Gated Sodium Channel subtype specific conditional knockout mice which provide invaluable tools for the development of therapeutics for the treatment of pain. {{end}}<h2>The Technology and its Advantages</h2>University...
Published: 9/17/2024   |   Inventor(s): John Wood
Keywords(s): Central Nervous System (CNS)
Category(s): Research Tools, Bioanalytics & Assays