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Search Results - c.v.+ramana
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Novel small molecule inhibitors of phosphatidylinositol-3,4,5-trisphosphate (PIP3)
Why is the target important?The PI3 lipid kinase (PI3K) pathway is an important target for anti-cancer drug development because:It’s activated by growth factors, oncogenes (RAS), GPCRs, etc. It regulates an array of critical cellular functions, including survival, proliferation, metabolism and cell motility. PI3K and its downstream effectors are...
Published: 3/19/2021
|
Inventor(s):
Alexei Degterev
,
Benchun Miao
,
C.v. Ramana
Keywords(s):
Category(s):
Diseases: cancer
,
Therapeutic: small molecule