Search Results - bryan+mcclellan

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Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
Targeting protein palmitoylation to suppress tumor growth and metastasis in triple negative breast cancer
Flotillin-1 palmitoylation is essential for its stability and tumor-promoting functions in triple-negative breast cancer (TNBC). Disrupting this process, either genetically or with targeted inhibitors, reduces tumor growth and metastasis, making it a potential therapeutic target. Background Triple negative breast cancer (TNBC) is a particularly aggressive...
Published: 4/16/2025   |   Inventor(s): Linda deGraffenried, Bryan McClellan
Keywords(s):  
Category(s): Life sciences > Therapeutics > Biologic