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Search Results - bryan+mcclellan
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Targeting protein palmitoylation to suppress tumor growth and metastasis in triple negative breast cancer
Flotillin-1 palmitoylation is essential for its stability and tumor-promoting functions in triple-negative breast cancer (TNBC). Disrupting this process, either genetically or with targeted inhibitors, reduces tumor growth and metastasis, making it a potential therapeutic target. Background Triple negative breast cancer (TNBC) is a particularly aggressive...
Published: 8/8/2024
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Inventor(s):
Linda deGraffenried
,
Bryan McClellan
Keywords(s):
Category(s):
Life sciences > Therapeutics > Biologic