Search Results - audrey+odom

3 Results Sort By:
MEPicides: Novel DXR Inhibitors for Drug-Resistant Malaria and Tuberculosis
Malaria and tuberculosis, caused by Plasmodium spp. and Mycobacterium tuberculosis respectively, continue to pose global health challenges with an estimated 429,000 deaths annually. While efforts have been underway to develop drugs targeting the causative agents behind these diseases, the rise of drug resistance strains of these pathogens has limited...
Published: 10/29/2024   |   Inventor(s): Cynthia Dowd, Darean Bague, Ruiqin Wang, Audrey Odom, Robin Couch, Helena Boshoff
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
Antibiotic for Veterinary Staphylococcal Infections
­New bacteriostatic compounds treat Staphylococcal strains that infect bovine, cat, and dog populations. Staphylococcal infections affect an estimated 20% of bovine populations in the dairy industry, and are the single largest indication for antibiotic use on dairy farms. Staphylococcal infections lead to a cost of greater than $1 billion per year...
Published: 9/11/2024   |   Inventor(s): Cynthia Dowd, Audrey Odom, Rachel Edwards, Kenneth Heidel, Xu "Jack" Wang, Rene Chofor
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
A new small molecule to kill drug-resistant malaria parasites
GW researchers synthesized the new small molecule, RCB-185, and initially showed efficacy against Mycobacterium tuberculosis (Mtb), but now demonstrate much higher efficacy against malaria. According to the World Health Organization, 2015 had 212 million cases of malaria with 429,000 deaths. People desperately need new treatments for malaria, as use...
Published: 9/11/2024   |   Inventor(s): Cynthia Dowd, Robert Brothers, Audrey Odom, Rachel Edwards
Keywords(s):  
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Small Molecules