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Prefusion Coronavirus Spike Proteins and Their Use
Coronaviruses (CoVs) can cause severe respiratory disease with high fatality rates in humans. The 2002-2003 SARS-CoV epidemic resulted in 8098 cases and 744 deaths, and MERS-CoV, which emerged in 2012, has resulted in 2144 cases and over 750 deaths as of March 2018. Currently, there are no effective prophylactic or therapeutic measures, and because...
Published: 10/28/2024
|
Inventor(s):
Masaru Kanekiyo
,
Michael Joyce
,
Kizzmekia Corbett
,
Hadi Yassine
,
Jason McLellan
,
Christopher Cottrell
,
Nianshuang Wang
,
Jesper Pallesen
,
Hannah Turner
,
Robert Kirchdoerfer
,
Andrew Ward
,
Barney Graham
Keywords(s):
CORONAVIRUS
,
DC5BXX
,
proteins
,
Stabilized
,
VACCINATION
Category(s):
Collaboration Sought > Collaboration
,
TherapeuticArea > Infectious Disease
,
Application > Vaccines