Search Results - andrew+griffith

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Antibodies to TMC1 Protein for Hearing Loss
This technology includes antibodies for TMC1 protein as a treatment for hearing loss. TMC1 is one of the common genes causing hereditary hearing loss. Our laboratory used synthetic peptides corresponding to the TMC1 protein to immunize rabbits. The resulting antisera were shown to bind to TMC1 protein expressed in heterologous expression systems. TMC1...
Published: 5/19/2025   |   Inventor(s): Andrew Griffith, Tomoko Makishima, Valentina Labay
Keywords(s):  
Category(s): Application > Research Materials, Application > Therapeutics, ResearchProducts > Antibodies, Collaboration Sought > Licensing, Collaboration Sought > Materials Available
TMC1, a Deafness-Related Gene
Hearing loss is a common communication disorder affecting nearly 1 in 1,000 children in the United States alone, and nearly 50% of adults by the age of eighty. Hearing loss can be caused by environmental and disease-related factors; however, hearing loss due to genetic factors accounts for approximately 50% of cases. The NIH announces the isolation...
Published: 10/28/2024   |   Inventor(s): Andrew Griffith
Keywords(s): Hereditary deafness, IA6XXX, IAXXXX, IB6XXX, IBXXXX, IXXXXX, UAXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Reproductive Health, TherapeuticArea > Rare/Neglected Diseases